The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

Cai‐Hong Yun; Kristen E. Mengwasser; Angela V. Toms; Michele Sue‐Ann Woo; Heidi Greulich; Kwok‐Kin Wong; Matthew Meyerson; Michael J. Eck

Năm xuất bản2008

Nguồn học thuậtProceedings of the National Academy of Sciences

Định danhDOI 10.1073/pnas.0709662105

TRÍCH DẪN ĐỀ XUẤTAPA 7

Cai‐Hong Yun; Kristen E. Mengwasser; Angela V. Toms; Michele Sue‐Ann Woo; Heidi Greulich; Kwok‐Kin Wong; Matthew Meyerson; Michael J. Eck (2008). The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proceedings of the National Academy of Sciences, 105(6), 2070-2075. https://doi.org/10.1073/pnas.0709662105

Thông tin thư mục

Nguồn/Tạp chí: Proceedings of the National Academy of Sciences
Tập: 105
Số: 6
Trang: 2070-2075
Nhà xuất bản: National Academy of Sciences
DOI: 10.1073/pnas.0709662105 ↗

Từ khóa

T790M; Gefitinib; Mutation; Mutant; Resistance mutation; Erlotinib; Mutagenesis; Biology; Kinase; Biochemistry; Chemistry; Epidermal growth factor receptor; Receptor